Mutational loss of sensitivity to mutacin GS-5 in Streptococcus pyogenes: characterization of a mutant deficient in receptor protein

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Mutational loss of sensitivity to mutacin GS-5 in Streptococcus pyogenes: characterization of a mutant deficient in receptor protein.

By means of a stepwise selection procedure, mutants capable of growing in the presence of relatively high multiplicities of a bacteriocin from Streptococcus mutans GS-5 were obtained from a sensitivie strain of Streptococcus pyogenes. Mutacin-neutralizing activity of cell extracts containing receptor protein was examined in one variant that adsorbed 1/6 the amount of bacteriocin adsorbed by the...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1980

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.17.2.151